{"id":9713,"date":"2026-07-07T13:17:44","date_gmt":"2026-07-07T13:17:44","guid":{"rendered":"https:\/\/unescoalfozanprize.org\/?p=9713"},"modified":"2026-07-07T13:17:44","modified_gmt":"2026-07-07T13:17:44","slug":"researchers-identify-a-new-driver-of-neuron-death-in-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/unescoalfozanprize.org\/zh-hans\/researchers-identify-a-new-driver-of-neuron-death-in-alzheimers-disease\/","title":{"rendered":"Researchers Identify a New Driver of Neuron Death in Alzheimer\u2019s Disease"},"content":{"rendered":"<p>Researchers from King&#8217;s College London have identified a previously overlooked mechanism that may explain how brain cells die in Alzheimer&#8217;s disease and frontotemporal dementia. The study found that toxic protein buildup can trigger a process called karyoptosis, causing the cell&#8217;s nucleus to shrink and break apart, ultimately leading to neuron death. Researchers also identified a key molecular pathway involved in this process, offering a potential new target for future treatments. The findings could help scientists develop therapies that slow the loss of brain cells, potentially delaying disease progression and preserving cognitive function for longer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from King&#8217;s College London have ident [&hellip;]<\/p>\n","protected":false},"author":12,"featured_media":9707,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[66],"tags":[],"class_list":["post-9713","post","type-post","status-publish","format-standard","hentry","category-66"],"_links":{"self":[{"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/posts\/9713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/comments?post=9713"}],"version-history":[{"count":1,"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/posts\/9713\/revisions"}],"predecessor-version":[{"id":9714,"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/posts\/9713\/revisions\/9714"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/media\/9707"}],"wp:attachment":[{"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/media?parent=9713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/categories?post=9713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/unescoalfozanprize.org\/zh-hans\/wp-json\/wp\/v2\/tags?post=9713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}